I don't know how popular the television show "The Big Bang Theory" is among young women - probably not very - and while that show does have a pretty but somewhat dumb blonde, it also has several actresses portraying women with doctorates in science.
Melissa Rauch portrays Howard's wife Bernadette, a doctorate level microbiologist with a well-paying job.
Mayim Bialik, who portrayed Blossom in the 90's, portrays neurobiologist Amy Farrah Fowler. In real life Mayim has a Ph.D. in neuroscience from UCLA. She speaks on a variety of topics besides acting, including to scientific and mathematical groups.
Sara Gilbert portrays the very sharp-tongued Dr. Leslie Winkle, a physicist.
Christine Baranaski, currently a regular on "The Good Wife", portrays Dr. Beverly Hofstadter, Leonard's mother. She plays a neuroscientist and a psychiatrist. I think she is hilarious.
These women are all brilliant, witty and funny, and are not the social misfits that the male characters are. So I think these are pretty good role models for women in STEM (Science, Technology, Engineering and Math).